TITULO FUENTE ORIGINAL: Ketamine and remifentanil interactions on the sevoflurane minimum alveolar concentration and acute opioid tolerance in the rat |
AUTORES: Aguado D, Abreu M, Benito J, García-Fernández J, Gómez de Segura IA |
REVISTA ABREV.: Anesth Analg |
AÑO: 2011 |
REFERENCIA: 113(3):505-12 |
DOI: 10.1213/ANE.0b013e318227517a |
RESUMEN ORIGINAL:
BACKGROUND:Ketamine is used at low doses for its analgesic and antihyperalgesic properties when combined with opioids but also when opioid-induced hyperalgesia and tolerance appear. In this study we determined the interaction of ketamine and remifentanil on the minimum alveolar concentration (MAC) of sevoflurane in rats and to determine whether ketamine may block acute opioid tolerance... + Leer más |