TITULO FUENTE ORIGINAL: Buprenorphine - an attractive opioid with underutilized potential in treatment of chronic pain |
AUTORES: Khanna IK0, Pillarisetti S |
REVISTA ABREV.: Journal of Pain Research |
AÑO: 2015 |
REFERENCIA: 8:859-70 |
DOI: 10.2147/JPR.S85951 |
RESUMEN ORIGINAL:
Despite proven clinical utility, buprenorphine has not been used widely for the treatment of chronic pain. Questions about "ceiling effect" or bell-shaped curve observed for analgesia in preclinical studies and potential withdrawal issues on combining with marketed μ-agonists continue to hinder progress in expanding full potential of buprenorphine in the treatment of cancer and noncancer... + Leer más |
ENLACES DE INTERÉS Enlace al pdf de acceso libre: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC[...] |