REVISTA

Una plataforma de detección fenotípica humana para el dolor crónico

Descripción: Los modelos humanos de dolor crónico fisiológicamente relevantes son esenciales para el desarrollo de nuevas terapias y para superar la mala traducción entre los estudios en animales y el entorno clínico

TITULO FUENTE ORIGINAL:

A humanized phenotypic screening platform for chronic pain

AUTORES:

Tams D, Karila P, Barnes A

REVISTA ABREV.:

Nat Methods

AÑO:

2017

REFERENCIA:

14, 636

DOI:

10.1038/nmeth.f.401

RESUMEN ORIGINAL:

Censo Biotechnologies and Cellectricon have joined forces to develop a first-in-kind humanized drug discovery platform to target chronic pain. The platform is based on human induced pluripotent stem cell–derived neurons in combination with Cellectricon's Cellaxess® Elektra screening system. The combination of highly functional screening with a human cell type of relevance for chronic... + Leer más

Censo Biotechnologies and Cellectricon have joined forces to develop a first-in-kind humanized drug discovery platform to target chronic pain. The platform is based on human induced pluripotent stem cell–derived neurons in combination with Cellectricon's Cellaxess® Elektra screening system. The combination of highly functional screening with a human cell type of relevance for chronic pain has the potential to enable the generation of better drug candidates for this condition and other diseases

- Leer menos

ENLACES DE INTERÉS

Enlace al pdf de acceso libre: https://www.nature.com/articles/nmeth.f.401.p[...]