REVISTA

Dexmedetomidina en el manejo del dolor agudo perioperatorio: un analgésico adyuvante

Descripción: La dexmedetomidina desempeña sus funciones analgésicas y analgésicas adyuvantes a través de múltiples mecanismos en cada etapa del período perioperatorio. La adición de dexmedetomidina a los anestésicos locales es una nueva vía prometedora para mejorar su efectividad

TITULO FUENTE ORIGINAL:

Dexmedetomidine in perioperative acute pain management: a non-opioid adjuvant analgesic

AUTORES:

Tang C, Xia Z

REVISTA ABREV.:

J Pain Res

AÑO:

2017

REFERENCIA:

10:1899-1904

DOI:

10.2147/JPR.S139387

RESUMEN ORIGINAL:

Many nociceptive, inflammatory, and neuropathic pathways contribute to perioperative pain. Although opioids have long been a mainstay for perioperative analgesia, other non-opioid therapies, and dexmedetomidine, in particular, have been increasingly used as part of a multimodal analgesic regimen to provide improved pain control while minimizing opioid-related side effects. This article reviews... + Leer más

Many nociceptive, inflammatory, and neuropathic pathways contribute to perioperative pain. Although opioids have long been a mainstay for perioperative analgesia, other non-opioid therapies, and dexmedetomidine, in particular, have been increasingly used as part of a multimodal analgesic regimen to provide improved pain control while minimizing opioid-related side effects. This article reviews the evidence supporting the preoperative, intraoperative, and postoperative efficacy of dexmedetomidine as an adjuvant, and the efficacy of intravenous, spinal canal, and nerve block analgesia with dexmedetomidine for perioperative acute pain treatment. While there have not been any large-scale clinical trials conducted, the current body of evidence suggests that dexmedetomidine is suitable for use as an adjuvant analgesic at all perioperative stages. However, there are potential adverse effects, such as hypotension and bradycardia, which must be taken into consideration by clinicians

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ENLACES DE INTERÉS

Enlace al pdf de acceso libre: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC[...]