REVISTA

Una revisión de los factores que afectan a la selección analgésica para grandes animales sometidos a investigación

Descripción: La optimización del bienestar animal y el valor de los datos científicos de estudios experimentales, requieren la capacidad de identificar, cuantificar y tratar el dolor animal mediante la aplicación de un conocimiento de farmacología analgésica que simpatiza con los objetivos del estudio

TITULO FUENTE ORIGINAL:

A review of factors affecting analgesic selection in large animals undergoing translational research

AUTORES:

R E Clutton

REVISTA ABREV.:

Vet J

AÑO:

2018

REFERENCIA:

236:12-22

DOI:

10.1016/j.tvjl.2018.04.006

RESUMEN ORIGINAL:

The widespread physiological effects of pain in experimental animals are likely to reduce the validity of data except when pain itself is studied. Appropriately prescribed analgesics will limit pain and improve the welfare of animals undergoing noxious experimental procedures. However, their injudicious use may also introduce variability in data and limit study reproducibility. Optimizing both... + Leer más

The widespread physiological effects of pain in experimental animals are likely to reduce the validity of data except when pain itself is studied. Appropriately prescribed analgesics will limit pain and improve the welfare of animals undergoing noxious experimental procedures. However, their injudicious use may also introduce variability in data and limit study reproducibility. Optimizing both animal welfare and the value of scientific data from experimental studies requires the ability to identify, quantify and treat animal pain by applying a knowledge of analgesic pharmacology that is sympathetic to study objectives. This review first examines the reasons for promoting analgesic use in translational animal research and, in focussing on pigs and small ruminants, then identifies factors that should be considered when devising analgesic plans

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