REVISTA

Comparación de dexmedetomidina o sufentanilo combinados con ropivacaína para la analgesia epidural después de la toracotomía: un estudio controlado al

Descripción: La dexmedetomidina combinada con ropivacaína puede proporcionar una mejor analgesia postoperatoria y efecto sedante en pacientes sometidos a cirugía torácica

TITULO FUENTE ORIGINAL:

Comparison of dexmedetomidine or sufentanil combined with ropivacaine for epidural analgesia after thoracotomy: a randomized controlled study

AUTORES:

M J Yan, T Wang, X M Wu , W Zhang

REVISTA ABREV.:

J Pain Res

AÑO:

2019

REFERENCIA:

12:2673-2678

DOI:

10.2147/JPR.S208014

RESUMEN ORIGINAL:

Background: Thoracotomy is frequently accompanied with moderate-to-severe postoperative pain, and excellent pain management is important for early rehabilitation. The purpose of this study is to investigate the effects of dexmedetomidine combined with ropivacaine for epidural analgesia after thoracotomy. Methods: One hundred and thirty patients undergoing elective lung lobectomy were... + Leer más

Background: Thoracotomy is frequently accompanied with moderate-to-severe postoperative pain, and excellent pain management is important for early rehabilitation. The purpose of this study is to investigate the effects of dexmedetomidine combined with ropivacaine for epidural analgesia after thoracotomy.

Methods: One hundred and thirty patients undergoing elective lung lobectomy were enrolled in the double-blind study and randomly divided into two groups. Group A received 0.5 µg/mL of dexmedetomidine plus 0.1% ropivacaine for postoperative analgesia, and group B (control group) received 0.5 µg/mL of sufentanil plus 0.1% ropivacaine for postoperative analgesia. Hemodynamic parameters were monitored. Pain intensity at rest was assessed using a visual analog scale (VAS) at 2, 4, 6,8, 12, 24, and 48 hrs postoperatively. Ramsay sedation score (RSS), analgesic consumption, postoperative respiratory depression, nausea and vomiting, pruritus, and bradycardia were recorded.

Results: The VAS values at rest during the postoperative 6-48 hrs were lower in group A than those in group B (P<0.05), and the RSS values were higher in group A during the postoperative 4-48 hrs compared to group B (P<0.05). Side effects were similar between the groups (P>0.05).

Conclusion: Dexmedetomidine combined with ropivacaine may provide better postoperative analgesia and sedative effect in patients undergoing thoracic surgery with fewer side effects. It is superior to sufentanil in analgesic effect during postoperative analgesia after thoracotomy

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Enlace al pdf de acceso libre: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC[...]