Calculadora de dosis para ratones (excel)

Calculating appropriate dilutions and doses for mouse injectable analgesics and anesthetics can be an intricate and time-consuming process. Determining the correct amount to administer to a mouse is dependent on several variables including animal weight, acceptable injection volume, and simultaneous administration of multiple drug agents. An inappropriate dilution or a miscalculated dose can... + Leer más

Calculating appropriate dilutions and doses for mouse injectable analgesics and anesthetics can be an intricate and time-consuming process. Determining the correct amount to administer to a mouse is dependent on several variables including animal weight, acceptable injection volume, and simultaneous administration of multiple drug agents. An inappropriate dilution or a miscalculated dose can result in excessive anesthesia or death of the animal. To simplify and streamline the process of mouse drug dilution and calculation, we have created an electronic dosage calculator in Microsoft Excel for administering injectable anesthetics and analgesics to mice. Following mouse weight, number of animals to inject, and the desired drug or drug combination inputs, the Mouse Dosage Calculator instantly displays the necessary stock and dilutant volumes to combine along with the working concentration of the preparation. All calculations were standardized to produce a final injection volume of 0.3mL. The calculator has been field tested by veterinary technicians within the University of California, San Francisco (UCSF) Laboratory Animal Resource Center on a range of mouse cases.

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